Hemophilia A is the most common hereditary disease associated with bleeding. It is caused be a decrease in amount or activity of factor VIII. Factor VIII is an important protein involved in the coagulation process, mainly in the intrinsic pathway. Hemophiliacs have a tendency to bruise easily, and have massive hemorrhage after trauma or surgical procedures. Recurrent bleeding in joints also occurs in people with this disease. When hemophiliacs bleed, they do not bleed faster than normal, they bleed longer because the coagulation process does not function properly. This condition can lead to death and may not be diagnosed until an autopsy is performed by medical personnel, such as forensic nurses.
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